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[5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. This is a news report of the research, so I can't learn the details of how the science was conducted. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. [6] Venditti P, Di Stefano L, Di Meo S: Oxidative stress in cold induced hyperthyroid state. Physician/Author on Facebook. However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. Cookie Notice [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. Yet Another Frankenfood Pandoras Box: the Majorit How Medical Science Proves that Black Is White. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. Clin Cancer Res 2011, 30:77. Gestionar el consentimiento de las cookies. Correlation is not causation. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be. You must log in or register to reply here. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. Is Drug-Based Medicine a Form of Human Sacrifice? It may not display this or other websites correctly. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Thanks, I am not suggesting I believe in all that I see. J Exp Biol 2010, 213:28992911. May be of interest: Study: Millions Treated for Hypothyroidism At Risk Due to excessive bot signups along with nefarious actors we are limiting forum registration. Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. Tokushima J Exp Med 1991, 38:2535. Based just on this article, I think the study's conclusion that Synthroid may cause an increase in lung cancer risk is premature. They found no significant correlation between T4 sales and breast, colorectal and gastric cancers, but did find a significant correlation for lung cancer (p < 0.05) corrected for smoking and age. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. In fact, it is the high levels of T4 that make them more susceptible to cancer. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called 'active ingredient' T4 versus the natural variations in hormone concentrations found in the 'real thing,' which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Forgot account? However, I do not believe it was out of the blue now. 1). Here members can share stories, find important information and learn from the experiences of others like themselves. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. I have always found this condition a riddle. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to replacement therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. A study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' 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MASA Traditional Tortilla Chips by Ancient Crunch, Vitamins, Minerals & Amino Acid Supplements, http://www.greenmedinfo.com/blog/study- ng-cancers, Patients' Perspectives On Refusing Diagnosis Or Treatment For Lung Cancer, Unintended Weight Loss Is The 2nd Highest Risk Factor For Certain Cancers, Stress Causes Genetic Mutations; Cancer Thrives Under Stress, Tetracyclines (and A Few Other Antibiotics) As A Cure For Cancer, Vitamin B May Increase Risk Of Lung Cancer In Men, Study Says, Biggest Study So Far Shows Aspirin Reduces Any Cancer Risk, Methylation Levels Can Predict Breast Cancer Risk, Vitamin A As A Powerful Treatment For Cancer, Screening For Testicular Cancer (a Review), For Many Cancers Early Diagnosis Can Actually Be Deadly, As Altitude Rises, Lung Cancer Rates Fall, The Anti Depression Pills that may Kill Cancer, Holy Grail Blood Test May Detect Cancer Before Tumors Form. millions treated for hypothyroidism at risk for lung cancer Cancer-related Fatigue in Lung Cancer: A Research Agenda: An Official Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). [15] [16] There is also the more logical option of support the body's thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. Angiology 2000, 51:S65S68. Kelly Mellott on LinkedIn: Nodify Lung: Nodule Risk Assessment | Biodesix I posted it to see what anyone had to add. Monaldi Arch Chest Dis 2003, 59:140145. Thus, I am monitored carefully. Lung cancer survivors support group and discussion community, http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-lung-cancers?utm_source=www.GreenMedInfo.com&utm_campaign=2189ddd3c1-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-2189ddd3c1-87046221. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. Endocrinol. millions treated for hypothyroidism at risk for lung cancer I'm not saying that there Is no link between Synthroid and lung cancer.